Biol. Pharm. Bull. 28(2) 224—225 (2005)
نویسندگان
چکیده
against several kind of sickness including cancer, gastric ulcers, dyspepsia and also useful as an antibacterial and antiinflammatory. Sesquiterpenes, triterpenes, quinone-methide and sesquiterpene pyridine alkaloids have been identified in these species. Maytenus obtusifolia MART. is a plant found in many states of the Northeast and South-east of Brazil, which is used in traditional medicine for the treatment of ulcer. A chemical study of chloroform extract (CE) of this plant showed the presence of triterpenes of the series friedelan, oleanane, ursane and one pyranoquinoline alkaloid. It is known that terpenes have actions pharmacological on animal behavior. Therefore it was made a preliminary screening which showed that the CE possesses a CNS depressant effect. In the present study, we report the neuroleptic activity of the CE of Maytenus obtusifolia MART. roots.
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